AnaesthesiaUK Journal

Modulation of remifentanil-induced postinfusion hyperalgesia by the �-blocker propranolol in humans

Wed, 09 May 2012 00:00:00 GMT

H3 PAcute and chronic exposure to opioids has been associated with hyperalgesia in both animals and humans. In humans, expansion of the area of mechanical hyperalgesia surrounding an experimentally induced lesion after the cessation of remifentanil infusion is a commonly used model of opioid hyperalgesia (remifentanil-induced postinfusion hyperalgesia; RPH). The ......
Pain - Pain 2012; 153: 974-81
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Objective assessment of the immediate postoperative analgesia using pupillary reflex measurement: a prospective and observational study

Wed, 09 May 2012 00:00:00 GMT

H3 PThe pupillary dilatation reflex (PDR) has been successfully used to assess the analgesic component of a balanced anaesthetic regimen. The authors hypothesised that PDR could be a reliable index of pain intensity and could guide morphine administration in the immediate postoperative period. P H3 H3 H3MethodsH3 PA total of 100 patients scheduled to ......
Pain - Anesthesiology 2012; 116: 1006-12
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Continuous spinal anesthesia for Cesarean hysterectomy and massive hemorrhage in a parturient with placenta increta

Wed, 09 May 2012 00:00:00 GMT

H3 PThese authors present a case of anaesthetic management using a continuous spinal anaesthesia (CSA) technique in a patient with placenta increta who underwent elective Caesarean hysterectomy with massive postpartum haemorrhage. P H3 H3 H3Clinical detailsH3 PA 34-year-old parturient (G3P2) was scheduled for Caesarean delivery and possible hysterectomy at 35(+3) weeks due to suspected ......
Obstetrics - Can J Anaesth 2012; 59: 473-7
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Potentially toxic concentrations in blood of total ropivacaine after bilateral transversus abdominis plane blocks; a pharmacokinetic study

Wed, 09 May 2012 00:00:00 GMT

H3 PElevated blood levels of lidocaine and ropivacaine have been described after transversus abdominis plane (TAP) block. These authors carried out a prospective observational pharmacokinetic study to investigate the pharmacokinetic profile of ropivacaine after bilateral TAP blocks. P H3 H3 H3Methods H3 PA total of 21 adult patients presenting for abdominopelvic surgery with bilateral ......
Obstetrics - Eur J Anaesthesiol 2012; 29: 235-8
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Unplanned endotracheal extubations in the intensive care unit: systematic review, critical appraisal, and evidence-based recommendations

Wed, 09 May 2012 00:00:00 GMT

H3 PThese authors carried out a study to update the state of knowledge on unplanned tracheal extubations in the intensive care unit. They focused on the following topics: incidence, risk factors, reintubation after unplanned extubation, outcomes and prevention. Based on their review, they made recommendations for preventing unplanned extubations. P H3 H3 H3MethodsH3 PElectronic ......
Intensive Care - Anesth Analg 2012; 114: 1003-14.
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Early treatment with risperidone for subsyndromal delirium after on-pump cardiac surgery in the elderly: a randomized trial

Wed, 09 May 2012 00:00:00 GMT

BRThe authors carried out a randomised, parallel-arm trial to study the effect of treating subsyndromal delirium with risperidone on the incidence of clinical delirium in elderly patients who underwent on-pump cardiac surgery. BR H3 H3 H3Methods H3A total of 101 patients, aged ?65 years, who experienced subsyndromal delirium after on-pump cardiac surgery ......
Intensive Care - Anesthesiology 2012; 116: 987-97
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High STOP-Bang score indicates a high probability of obstructive sleep apnoea

Wed, 09 May 2012 00:00:00 GMT

H3 PThe STOP-Bang questionnaire is used to screen patients for obstructive sleep apnoea (OSA). Theses authors investigated the association between STOP-Bang scores and the probability of OSA. P H3 H3 H3MethodsH3 PPatients who were scheduled to undergo inpatient surgery were asked to answer the STOP questionnaire, and then undergo either laboratory or portable polysomnography ......
Anaesthesia - Br J Anaesth 2012; 108: 768-75
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Perioperative management of hereditary arrhythmogenic syndromes

Wed, 09 May 2012 00:00:00 GMT

H3 PPatients with inherited cardiac channel disorders are at high risk of perioperative lethal arrhythmias. Preoperative control of symptoms, a multidisciplinary approach, good haemodynamic monitoring, adequate anaesthesia and analgesia, perioperative maintenance of normocarbia, normothermia and normovolaemia are all important. In congenital long QT syndrome, torsades de pointes should be prevented ......
Anaesthesia - Br J Anaesth 2012; 108: 730-44
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�-Opioid receptor gene A118G polymorphism predicts survival in patients with breast cancer

Wed, 11 Apr 2012 00:00:00 GMT

studies suggest that opioids may promote tumour growth. Genetic polymorphisms have been shown to affect opioid receptor function and to modify the clinical effects of morphine. These authors studied the association between six common polymorphisms in the �-opioid receptor gene, including the A118G polymorphism, and east cancer survival. BRBRP H3MethodsH3 P ......
Pain - Anesthesiology 2012; 116: 896-902
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A comparison of epidural analgesia and traditional pain management effects on survival and cancer recurrence after colectomy: a population-based study

Wed, 11 Apr 2012 00:00:00 GMT

H3 PCancer recurrence after surgery may be affected by immunosuppressive factors such as surgical stress, anaesthetic drugs and opioids. By limiting exposure to these, epidural analgesia may enhance tumour surveillance. These authors compared survival and cancer recurrence rates for resection of colorectal cancer between patients who received perioperative epidurals and ......
Pain - Anesthesiology 2012; 116: 797-806
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